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整合素β6/Integrin β6抗体

Host:RabbitTarget Protein:Integrin beta 6IR:Immunogen Range:351-450/788Clonality:PolyclonalIsotype:IgGEntrez Gene:3694Swiss Prot:P18564Source:KLH conjugated synthetic peptide derived from human Integrin beta 6:351-450/788 Purification:affinity purified by Protein AStorage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.Background:Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

DNAJC12 Polyclonal ANTIBODY

Basic InformationSize:130 μg/mlSource:RabbitIsotype:IgGPurification Method:Antigen affinity purificationImmunogen Catalog Number:AG2989GenBank Accession Number:BC017018GeneID (NCBI):56521Full Name:DnaJ (Hsp40) homolog, subfamily C, member 12Calculated MW:198aa,23 kDaObserved MW:23 kDaRecommended Dilutions: WB 1:500-1:1000                                          IHC 1:20-1:200ApplicationsTested Applications:IHC, WB, ELISACited Applications:IF, WBSpecies Specificity:human,mouse,ratCited Species:humanPositive Controls:WB : A549 cells; HEK-293 cellsIHC : human pancreas cancer tissue;Background InformationNotable Publications Author Pubmed ID Journal ApplicationChoi Jin J 24122553 Cell Stress Chaperones WB,IFStorageStorage:Store at -20oC. Stable for one year after shipment.Storage Buffer:PBSwith 0.1%sodium azide and 50%glycerol pH 7.3.Aliquoting is unnecessary for -20oC storage

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